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Circular Dichroism and Vibrational CD

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Overview


Jasco opens the door to the future of Circular Dichroism
JASCO has produced the highest quality circular dichroism instrumentation for over 50 years. The J-1000 series is the result of many advances in technology combined with a great deal of customer input. These three new models are adaptable to meet any requirements and can be expanded as applications or budgets evolve.

Features of the J-1000 series 
The three models of the J-1000 series offer the most robust feature set available, for applications ranging from education and routine analysis to complex research with strict requirements. 

Jasco FVS-6000 Vibrational Circular Dichroism spectrometer
In this brochure, Jasco introduces FVS-6000, a high performance VCD spectrometer.

CD measurement of protein film samples in the vacuum UV region
Marker bands for specific secondary structures are most typically observed in the UV region below 260 nm and as far into the far-UV region as possible. It has been widely reported that CD measurements using synchroton radiation have been used to successfully measure spectra down to around 140 nm. As an alternative to synchrotron radiation, the J-1500 CD spectrometer has been improved for measurements in the vacuum UV region.

CD measurement of α-pinene gas in the vacuum-UV region
This application note demonstrates that spectra of gas samples can be obtained using the J-1500 CD spectrometer with high signal-to-noise in the vacuum UV region.

Change in the fluorescence anisotropy spectrum by the denaturation of α-lactalbumin by guanadinium hydrochloride
This application note describes the use of the Jasco J-1500 CD spectrometer to measure fluorescence anisotropy. 

High-throughput CD spectral measurement for the evaluation of pH dependency of biomedicines
In this application note, JASCO demonstrates the use of the ASU-800 automated system to evaluate the pH dependency on the structure of human serum albumin (HSA).

Evaluation of structural change and thermal stability of Bovine IgG
In this application note, CD spectra measurement of Bovine IgG / phosphate buffer solution was performed using Temperature Interval Scan Measurement Program Program and a short path length cylindrical cylindrical cell. Measurement temperature was set from 20ºC to 95ºC.

Vibrational Circular Dichroism spectra using the Jasco FVS-6000
Measurement results of typical chiral compounds and hemoglobin as a model protein.

Application notes

CD measurement of protein film samples in the vacuum UV region
Marker bands for specific secondary structures are most typically observed in the UV region below 260 nm and as far into the far-UV region as possible. It has been widely reported that CD measurements using synchroton radiation have been used to successfully measure spectra down to around 140 nm. As an alternative to synchrotron radiation, the J-1500 CD spectrometer has been improved for measurements in the vacuum UV region.

High-throughput CD spectral measurement for the evaluation of pH dependency of biomedicines
Date of creation: 
22 February 2017
Library code: 
10770
Change in the fluorescence anisotropy spectrum by the denaturation of α-lactalbumin by guanadinium hydrochloride
Date of creation: 
22 February 2017
Library code: 
10768
CD measurement of α-pinene gas in the vacuum UV region
Date of creation: 
21 February 2017
Library code: 
10767
Measurement of the complex forming reaction of nickel sulfate and Rochelle salt probed by stopped-flow CD spectroscopy
Date of creation: 
21 February 2017
Library code: 
10765
Evaluation of structural change and thermal stability of Bovine IgG
Date of creation: 
28 January 2017
Library code: 
10728
Measurement of Vibrational Circular Dichroism spectra using the Jasco FVS-6000
Date of creation: 
30 January 2017
Library code: 
10735
Highly sensitive detection of DL-flavanone with circular dichroism (CD) detector
Date of creation: 
3 January 2017
Library code: 
10708
CD spectrum and CD chromatogram measurement of warfarin using J-1500
Date of creation: 
31 July 2017
Library code: 
11155
Temperature control and CD/fluorescence spectrum of lysozyme using temperature/wavelength scan measurement program
Date of creation: 
31 July 2017
Library code: 
11156
Literature

Features of the J-1000 series 
The three models of the J-1000 series offer the most robust feature set available, for applications ranging from education and routine analysis to complex research with strict requirements. 

Jasco VFT-4000 Vibrational Circular Dichroism attachment
Date of creation: 
10 July 2017
Library code: 
11055
J-1000 series Circular Dichroism spectrometers
Date of creation: 
22 October 2016
Library code: 
10668
Jasco FVS-6000 Vibrational Circular Dichroism spectrometer, an essential tool for absolute configuration of molecules
Date of creation: 
17 October 2016
Library code: 
10666
CD thermal denaturation measurement of minute sample volumes
Date of creation: 
12 June 2017
Library code: 
10944
Program of JWMVS-529 CD multivariate SSE analysis
Date of creation: 
12 June 2017
Library code: 
10950
Measurement of dichroic mirror using automated absolute reflectance measurement system
Date of creation: 
12 June 2017
Library code: 
10943
Multivariate SSE program
Date of creation: 
13 June 2017
Library code: 
10955
Secondary structure estimation (SSE) program of multiple samples
Date of creation: 
13 June 2017
Library code: 
10957