Analysis of polystyrene oligomers by semi-micro GPC

Semi-micro analysis has the advantage in cutting cost by reducing the consumption of mobile phase. Columns with smaller particle sizes and reduced column dimensions are ideal for rapid high performance analysis and provide economical and ecological advantages in reducing the consumption of organic solvent in GPC analysis.

Using these more efficient columns together with a faster response detector, which can detect the sharper eluted peaks, offers a shorter measurement time. The RI-4035 refractive index detector with small flow cell volume is optimized for high-speed data acquisition for use in semi-micro scale analysis using columns with high performance packing material with smaller particles.

This report shows polystyrene oligomer analysis using a GPC column designed for high-performance analysis. Analysis using the LC-4000 Series RHPLC system results in a 30% solvent saving compared to conventional separations.