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Extraction of phthalates in commercial milk products using ISOLUTE SLE+ Supported Liquid Extraction columns prior to LC-(+) APCI-MS/MS analysis

Resource type: 
Application note
Author(s): 
Biotage
Format: 
pdf
Date of creation: 
23 October 2017
Library code: 
11324

ISOLUTE SLE+ Supported Liquid Extraction plates and columns offer an efficient alternative to traditional liquid-liquid extraction (LLE) for bioanalytical sample preparation, providing high analyte recoveries, no emulsion formation and significantly reduced sample preparation time.

This application note describes a novel sample cleanup strategy to address the complex matrix effects associated with commercial milk product variables while maintaining adequate analyte recovery and repeatability.