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Extraction of synthetic cannabinoids (SPICE) from oral fluid using ISOLUTE SLE+ 96-well plates and columns prior to LC-MS/MS

Resource type: 
Application note
Author(s): 
Biotage
Format: 
pdf
Date of creation: 
23 October 2017
Library code: 
11329

ISOLUTE SLE+ Supported Liquid Extraction plates and columns offer an efficient alternative to traditional liquid-liquid extraction (LLE) for bioanalytical sample preparation, providing high analyte recoveries, no emulsion formation and significantly reduced sample preparation time.

This application note describes the extraction of a range of SPICE drugs and metabolites from neat oral fluid and oral fluid from a commercial collection kit using ISOLUTE SLE+ in both 96-well plate and column formats.