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Extraction of illicit drugs from hemolyzed whole blood using ISOLUTE SLE+ columns prior to LC-MS/MS analysis

Resource type: 
Application note
Author(s): 
Biotage
Format: 
pdf
Date of creation: 
23 October 2017
Library code: 
11330

ISOLUTE SLE+ Supported Liquid Extraction plates and columns offer an efficient alternative to traditional liquid-liquid extraction (LLE) for bioanalytical sample preparation, providing high analyte recoveries, no emulsion formation and significantly reduced sample preparation time.

This application note describes the extraction of different drugs in hemolyzed whole blood, which are typically screened for forensic toxicology panels, using ISOLUTE SLE+ supported liquid extraction columns in the 1 mL and 2 mL sample capacity formats.