Extraction of nicotine and metabolites from urine, serum, plasma and whole blood using ISOLUTE SLE+ prior to LC-MS/MS analysis
Resource type:
Application note
Format:
pdf
Date of creation:
23 October 2017
Library code:
11331
ISOLUTE SLE+ products provide clean, rapid, robust, efficient, high throughput and automatable extraction solutions for a wide range of analytes.
This application note describes a Supported Liquid Extraction (SLE) protocol for the extraction of nicotine, cotinine, 3-OH-cotinine, nornicotine, norcotinine and anabasine from urine, serum, plasma and whole blood using ISOLUTE SLE+ plates with LC-MS/MS detection.
