SICRIT HRMS for exhaled breath analysis

MS-based breath analysis is one of the youngest research areas in biomedical diagnostics. For patients, the non-invasive testing is very comfortable and diagnostic findings can be obtained in real-time. The analytical power of HR-MS for metabolite and biomarker identifcation is unquestioned, however, the plug&play design of SICRIT now drastically facilitates the interfacing setup with the MS-instrument. Furthermore, easy combination of the SICRIT Ion Source with chromatography or liquid injection is possible. Thus, complementary analysis of other biological matrix on the same MS may result in unique data for wide-ranging research and diagnostic tasks.

This application note shows how easily the SICRIT Ion source can be adapted to high-resolution MS instruments for trace analysis of biomarkers and metabolites in exhaled breath.