Norlab

Your partner in Northern Europe for innovative laboratory instruments

Extraction of NSAIDs from plasma using ISOLUTE SLE+

Resource type: 
Technical note
Author(s): 
Biotage
Format: 
pdf
Date of creation: 
23 August 2017
Library code: 
11225

Comparison of Biotage Extrahera vs. manual sample processing using a vacuum manifold

Automated sample preparation using the Biotage Extrahera was compared to an equivalent manual method utilizing a vacuum manifold. A selection of non-steroidal anti-inflammatory drugs (NSAIDS) were extracted from pooled stripped plasma using a supported liquid extraction procedure. ISOLUTE SLE+ 400 uL sample volume plates, part number 820-0400-P01 were used for extraction. Resulting extracts from both sample preparation methods were subsequently analyzed by LC-MS/MS.