Norlab

Your partner in Northern Europe for innovative laboratory instruments

Extraction of antiepileptic drugs from serum and urine using ISOLUTE SLE+ prior to LC-MS/MS analysis

Resource type: 
Application note
Author(s): 
Biotage
Format: 
pdf
Date of creation: 
23 October 2017
Library code: 
11321

ISOLUTE SLE+ Supported Liquid Extraction plates and columns offer an efficient alternative to traditional liquid-liquid extraction (LLE) for bioanalytical sample preparation, providing high analyte recoveries, no emulsion formation and significantly reduced sample preparation time.

This application note describes the extraction of neutral and zwitterionic antiepileptic drugs fortified in serum and urine using ISOLUTE SLE+ in a 96-well plate format.