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Extraction of acrylamide from fried potato chips (crisps) using ISOLUTE SLE+ prior to LC-MS/MS analysis

Resource type: 
Application note
Author(s): 
Biotage
Format: 
pdf
Date of creation: 
23 October 2017
Library code: 
11326

ISOLUTE SLE+ products provide clean, rapid, robust and efficient extraction solutions for a wide range of analytes.

This application note describes a Supported Liquid Extraction (SLE) protocol for the extraction of acrylamide from potato chips/crisps using ISOLUTE SLE+ columns with LC-MS/MS detection. The method described achieves high recoveries of acrylamide in fried potato chips (crisps). The method is sensitive enough to measure levels as low as 10 ppb in a popular brand and flavor and has also been tested in flavored varieties that were both machine and hand fried.