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Extraction of THC, Hydroxy-THC and Carboxy-THC from whole blood using ISOLUTE SLE+ prior to GC-MS analysis

Resource type: 
Application note
Author(s): 
Biotage (application note 840)
Format: 
pdf
Date of creation: 
14 January 2016
Library code: 
10587

This application note describes the extraction of Δ9-THC, 11-hydroxy- Δ9-THC and 11-nor-9-carboxy-THC from whole blood matrix, prior to GC/MS analysis. An extremely simple sample pre-treatment and extraction method is employed to extract the parent THC and main metabolites from complex whole blood matrix, delivering high, reproducible analyte recoveries.